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Differentiate w.r.t. x_50
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\frac{330x_{1000}^{2}x_{50}}{160}
Multiply x_{1000} and x_{1000} to get x_{1000}^{2}.
\frac{33}{16}x_{1000}^{2}x_{50}
Divide 330x_{1000}^{2}x_{50} by 160 to get \frac{33}{16}x_{1000}^{2}x_{50}.