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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(x\times 16)
Calculate -2 to the power of 4 and get 16.
16x^{1-1}
The derivative of ax^{n} is nax^{n-1}.
16x^{0}
Subtract 1 from 1.
16\times 1
For any term t except 0, t^{0}=1.
16
For any term t, t\times 1=t and 1t=t.
x\times 16
Calculate -2 to the power of 4 and get 16.