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-\frac{1}{4}\times 216000000000+6\times 6000^{2}-6\times 6000-280
Calculate 6000 to the power of 3 and get 216000000000.
\frac{-216000000000}{4}+6\times 6000^{2}-6\times 6000-280
Express -\frac{1}{4}\times 216000000000 as a single fraction.
-54000000000+6\times 6000^{2}-6\times 6000-280
Divide -216000000000 by 4 to get -54000000000.
-54000000000+6\times 36000000-6\times 6000-280
Calculate 6000 to the power of 2 and get 36000000.
-54000000000+216000000-6\times 6000-280
Multiply 6 and 36000000 to get 216000000.
-53784000000-6\times 6000-280
Add -54000000000 and 216000000 to get -53784000000.
-53784000000-36000-280
Multiply 6 and 6000 to get 36000.
-53784036000-280
Subtract 36000 from -53784000000 to get -53784036000.
-53784036280
Subtract 280 from -53784036000 to get -53784036280.