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\frac{8xy}{\left(-4\right)^{2}x^{2}}\left(-2\right)x^{3}
Expand \left(-4x\right)^{2}.
\frac{8xy}{16x^{2}}\left(-2\right)x^{3}
Calculate -4 to the power of 2 and get 16.
\frac{y}{2x}\left(-2\right)x^{3}
Cancel out 8x in both numerator and denominator.
\frac{-y\times 2}{2x}x^{3}
Express \frac{y}{2x}\left(-2\right) as a single fraction.
\frac{-y}{x}x^{3}
Cancel out 2 in both numerator and denominator.
\frac{-yx^{3}}{x}
Express \frac{-y}{x}x^{3} as a single fraction.
-yx^{2}
Cancel out x in both numerator and denominator.
\frac{8xy}{\left(-4\right)^{2}x^{2}}\left(-2\right)x^{3}
Expand \left(-4x\right)^{2}.
\frac{8xy}{16x^{2}}\left(-2\right)x^{3}
Calculate -4 to the power of 2 and get 16.
\frac{y}{2x}\left(-2\right)x^{3}
Cancel out 8x in both numerator and denominator.
\frac{-y\times 2}{2x}x^{3}
Express \frac{y}{2x}\left(-2\right) as a single fraction.
\frac{-y}{x}x^{3}
Cancel out 2 in both numerator and denominator.
\frac{-yx^{3}}{x}
Express \frac{-y}{x}x^{3} as a single fraction.
-yx^{2}
Cancel out x in both numerator and denominator.