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Differentiate w.r.t. a
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5\times 8a^{5-1}+3\left(-14\right)a^{3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
40a^{5-1}+3\left(-14\right)a^{3-1}
Multiply 5 times 8.
40a^{4}+3\left(-14\right)a^{3-1}
Subtract 1 from 5.
40a^{4}-42a^{3-1}
Multiply 3 times -14.
40a^{4}-42a^{2}
Subtract 1 from 3.