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72\left(6-\left(2-\frac{x}{4}+3\times \frac{x}{8}\right)\right)-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
Multiply both sides of the equation by 72, the least common multiple of 4,8,9,3.
72\left(6-\left(2-\frac{x}{4}+\frac{3x}{8}\right)\right)-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
Express 3\times \frac{x}{8} as a single fraction.
72\left(6-\left(2-\frac{2x}{8}+\frac{3x}{8}\right)\right)-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of 4 and 8 is 8. Multiply \frac{x}{4} times \frac{2}{2}.
72\left(6-\left(2+\frac{-2x+3x}{8}\right)\right)-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
Since -\frac{2x}{8} and \frac{3x}{8} have the same denominator, add them by adding their numerators.
72\left(6-\left(2+\frac{x}{8}\right)\right)-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
Combine like terms in -2x+3x.
72\left(6-2-\frac{x}{8}\right)-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
To find the opposite of 2+\frac{x}{8}, find the opposite of each term.
72\left(4-\frac{x}{8}\right)-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
Subtract 2 from 6 to get 4.
288-72\times \frac{x}{8}-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
Use the distributive property to multiply 72 by 4-\frac{x}{8}.
288-9x-648\left(\frac{5x}{9}+\frac{x}{3}\right)=144-72x
Cancel out 8, the greatest common factor in 72 and 8.
288-9x-648\left(\frac{5x}{9}+\frac{3x}{9}\right)=144-72x
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of 9 and 3 is 9. Multiply \frac{x}{3} times \frac{3}{3}.
288-9x-648\times \frac{5x+3x}{9}=144-72x
Since \frac{5x}{9} and \frac{3x}{9} have the same denominator, add them by adding their numerators.
288-9x-648\times \frac{8x}{9}=144-72x
Combine like terms in 5x+3x.
288-9x-72\times 8x=144-72x
Cancel out 9, the greatest common factor in 648 and 9.
288-9x-576x=144-72x
Multiply 72 and 8 to get 576.
288-585x=144-72x
Combine -9x and -576x to get -585x.
288-585x+72x=144
Add 72x to both sides.
288-513x=144
Combine -585x and 72x to get -513x.
-513x=144-288
Subtract 288 from both sides.
-513x=-144
Subtract 288 from 144 to get -144.
x=\frac{-144}{-513}
Divide both sides by -513.
x=\frac{16}{57}
Reduce the fraction \frac{-144}{-513} to lowest terms by extracting and canceling out -9.