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Differentiate w.r.t. x_5
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\frac{\mathrm{d}}{\mathrm{d}x_{5}}(4-35x_{5})
Multiply -1 and 35 to get -35.
-35x_{5}^{1-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-35x_{5}^{0}
Subtract 1 from 1.
-35
For any term t except 0, t^{0}=1.
4-35x_{5}
Multiply -1 and 35 to get -35.