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343-\left(a^{3}+12a^{2}+48a+64\right)
Use binomial theorem \left(p+q\right)^{3}=p^{3}+3p^{2}q+3pq^{2}+q^{3} to expand \left(a+4\right)^{3}.
343-a^{3}-12a^{2}-48a-64
To find the opposite of a^{3}+12a^{2}+48a+64, find the opposite of each term.
279-a^{3}-12a^{2}-48a
Subtract 64 from 343 to get 279.
343-\left(a^{3}+12a^{2}+48a+64\right)
Use binomial theorem \left(p+q\right)^{3}=p^{3}+3p^{2}q+3pq^{2}+q^{3} to expand \left(a+4\right)^{3}.
343-a^{3}-12a^{2}-48a-64
To find the opposite of a^{3}+12a^{2}+48a+64, find the opposite of each term.
279-a^{3}-12a^{2}-48a
Subtract 64 from 343 to get 279.