Differentiate w.r.t. x_4
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24x_{4}^{1-1}
The derivative of ax^{n} is nax^{n-1}.
24x_{4}^{0}
Subtract 1 from 1.
24\times 1
For any term t except 0, t^{0}=1.
24
For any term t, t\times 1=t and 1t=t.