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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(-2x^{2}+5x-9)
Combine 2x^{2} and -4x^{2} to get -2x^{2}.
2\left(-2\right)x^{2-1}+5x^{1-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-4x^{2-1}+5x^{1-1}
Multiply 2 times -2.
-4x^{1}+5x^{1-1}
Subtract 1 from 2.
-4x^{1}+5x^{0}
Subtract 1 from 1.
-4x+5x^{0}
For any term t, t^{1}=t.
-4x+5\times 1
For any term t except 0, t^{0}=1.
-4x+5
For any term t, t\times 1=t and 1t=t.
-2x^{2}+5x-9
Combine 2x^{2} and -4x^{2} to get -2x^{2}.