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Differentiate w.r.t. x
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-\frac{7}{2}\times 2x^{-\frac{7}{2}-1}
The derivative of ax^{n} is nax^{n-1}.
-7x^{-\frac{7}{2}-1}
Multiply -\frac{7}{2} times 2.
-7x^{-\frac{9}{2}}
Subtract 1 from -\frac{7}{2}.