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2\left(x^{2}+9\right)\left(x^{2}+10x+25\right)\left(x-16\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+5\right)^{2}.
\left(2x^{2}+18\right)\left(x^{2}+10x+25\right)\left(x-16\right)
Use the distributive property to multiply 2 by x^{2}+9.
\left(2x^{4}+20x^{3}+68x^{2}+180x+450\right)\left(x-16\right)
Use the distributive property to multiply 2x^{2}+18 by x^{2}+10x+25 and combine like terms.
2x^{5}-12x^{4}-252x^{3}-908x^{2}-2430x-7200
Use the distributive property to multiply 2x^{4}+20x^{3}+68x^{2}+180x+450 by x-16 and combine like terms.
2\left(x^{2}+9\right)\left(x^{2}+10x+25\right)\left(x-16\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+5\right)^{2}.
\left(2x^{2}+18\right)\left(x^{2}+10x+25\right)\left(x-16\right)
Use the distributive property to multiply 2 by x^{2}+9.
\left(2x^{4}+20x^{3}+68x^{2}+180x+450\right)\left(x-16\right)
Use the distributive property to multiply 2x^{2}+18 by x^{2}+10x+25 and combine like terms.
2x^{5}-12x^{4}-252x^{3}-908x^{2}-2430x-7200
Use the distributive property to multiply 2x^{4}+20x^{3}+68x^{2}+180x+450 by x-16 and combine like terms.