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Differentiate w.r.t. t
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16t^{1-1}+4\times 4t^{4-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
16t^{0}+4\times 4t^{4-1}
Subtract 1 from 1.
16t^{0}+16t^{4-1}
Multiply 4 times 4.
16t^{0}+16t^{3}
Subtract 1 from 4.
16\times 1+16t^{3}
For any term t except 0, t^{0}=1.
16+16t^{3}
For any term t, t\times 1=t and 1t=t.