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Differentiate w.r.t. x
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\frac{3}{10}\times 16x^{\frac{3}{10}-1}
The derivative of ax^{n} is nax^{n-1}.
\frac{24}{5}x^{\frac{3}{10}-1}
Multiply \frac{3}{10} times 16.
\frac{24}{5}x^{-\frac{7}{10}}
Subtract 1 from \frac{3}{10}.