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16x^{2}-\left(25y^{2}+10yz+z^{2}\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(5y+z\right)^{2}.
16x^{2}-25y^{2}-10yz-z^{2}
To find the opposite of 25y^{2}+10yz+z^{2}, find the opposite of each term.
16x^{2}-\left(25y^{2}+10yz+z^{2}\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(5y+z\right)^{2}.
16x^{2}-25y^{2}-10yz-z^{2}
To find the opposite of 25y^{2}+10yz+z^{2}, find the opposite of each term.