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Differentiate w.r.t. x
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3\left(-3\right)x^{3-1}+5\left(-1\right)x^{5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-9x^{3-1}+5\left(-1\right)x^{5-1}
Multiply 3 times -3.
-9x^{2}+5\left(-1\right)x^{5-1}
Subtract 1 from 3.
-9x^{2}-5x^{5-1}
Multiply 5 times -1.
-9x^{2}-5x^{4}
Subtract 1 from 5.