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\left(-x\right)x+4\left(-x\right)-3x\left(x+4\right)
Use the distributive property to multiply -x by x+4.
-x^{2}+4\left(-1\right)x-3x\left(x+4\right)
Multiply x and x to get x^{2}.
-x^{2}-4x-3x\left(x+4\right)
Multiply 4 and -1 to get -4.
-x^{2}-4x-3x^{2}-12x
Use the distributive property to multiply -3x by x+4.
-4x^{2}-4x-12x
Combine -x^{2} and -3x^{2} to get -4x^{2}.
-4x^{2}-16x
Combine -4x and -12x to get -16x.
\left(-x\right)x+4\left(-x\right)-3x\left(x+4\right)
Use the distributive property to multiply -x by x+4.
-x^{2}+4\left(-1\right)x-3x\left(x+4\right)
Multiply x and x to get x^{2}.
-x^{2}-4x-3x\left(x+4\right)
Multiply 4 and -1 to get -4.
-x^{2}-4x-3x^{2}-12x
Use the distributive property to multiply -3x by x+4.
-4x^{2}-4x-12x
Combine -x^{2} and -3x^{2} to get -4x^{2}.
-4x^{2}-16x
Combine -4x and -12x to get -16x.