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Differentiate w.r.t. a
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\frac{\mathrm{d}}{\mathrm{d}a}(-a^{8})
To raise a power to another power, multiply the exponents. Multiply 4 and 2 to get 8.
8\left(-1\right)a^{8-1}
The derivative of ax^{n} is nax^{n-1}.
-8a^{8-1}
Multiply 8 times -1.
-8a^{7}
Subtract 1 from 8.