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Differentiate w.r.t. x
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\left(x^{\frac{1}{2}}y^{-\frac{2}{3}}\right)^{-\frac{5}{4}}
Fraction \frac{-2}{3} can be rewritten as -\frac{2}{3} by extracting the negative sign.
\left(x^{\frac{1}{2}}\right)^{-\frac{5}{4}}\left(y^{-\frac{2}{3}}\right)^{-\frac{5}{4}}
Expand \left(x^{\frac{1}{2}}y^{-\frac{2}{3}}\right)^{-\frac{5}{4}}.
x^{-\frac{5}{8}}\left(y^{-\frac{2}{3}}\right)^{-\frac{5}{4}}
To raise a power to another power, multiply the exponents. Multiply \frac{1}{2} and -\frac{5}{4} to get -\frac{5}{8}.
x^{-\frac{5}{8}}y^{\frac{5}{6}}
To raise a power to another power, multiply the exponents. Multiply -\frac{2}{3} and -\frac{5}{4} to get \frac{5}{6}.