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\left(x^{2}+x+4x+4\right)\left(x-1\right)\left(x-4\right)
Apply the distributive property by multiplying each term of x+4 by each term of x+1.
\left(x^{2}+5x+4\right)\left(x-1\right)\left(x-4\right)
Combine x and 4x to get 5x.
\left(x^{3}-x^{2}+5x^{2}-5x+4x-4\right)\left(x-4\right)
Apply the distributive property by multiplying each term of x^{2}+5x+4 by each term of x-1.
\left(x^{3}+4x^{2}-5x+4x-4\right)\left(x-4\right)
Combine -x^{2} and 5x^{2} to get 4x^{2}.
\left(x^{3}+4x^{2}-x-4\right)\left(x-4\right)
Combine -5x and 4x to get -x.
x^{4}-4x^{3}+4x^{3}-16x^{2}-x^{2}+4x-4x+16
Apply the distributive property by multiplying each term of x^{3}+4x^{2}-x-4 by each term of x-4.
x^{4}-16x^{2}-x^{2}+4x-4x+16
Combine -4x^{3} and 4x^{3} to get 0.
x^{4}-17x^{2}+4x-4x+16
Combine -16x^{2} and -x^{2} to get -17x^{2}.
x^{4}-17x^{2}+16
Combine 4x and -4x to get 0.
\left(x^{2}+x+4x+4\right)\left(x-1\right)\left(x-4\right)
Apply the distributive property by multiplying each term of x+4 by each term of x+1.
\left(x^{2}+5x+4\right)\left(x-1\right)\left(x-4\right)
Combine x and 4x to get 5x.
\left(x^{3}-x^{2}+5x^{2}-5x+4x-4\right)\left(x-4\right)
Apply the distributive property by multiplying each term of x^{2}+5x+4 by each term of x-1.
\left(x^{3}+4x^{2}-5x+4x-4\right)\left(x-4\right)
Combine -x^{2} and 5x^{2} to get 4x^{2}.
\left(x^{3}+4x^{2}-x-4\right)\left(x-4\right)
Combine -5x and 4x to get -x.
x^{4}-4x^{3}+4x^{3}-16x^{2}-x^{2}+4x-4x+16
Apply the distributive property by multiplying each term of x^{3}+4x^{2}-x-4 by each term of x-4.
x^{4}-16x^{2}-x^{2}+4x-4x+16
Combine -4x^{3} and 4x^{3} to get 0.
x^{4}-17x^{2}+4x-4x+16
Combine -16x^{2} and -x^{2} to get -17x^{2}.
x^{4}-17x^{2}+16
Combine 4x and -4x to get 0.