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x^{2}+8x+16-2y\left(x-4\right)-\left(x+4\right)\left(y-x\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+4\right)^{2}.
x^{2}+8x+16-2y\left(x-4\right)-\left(xy-x^{2}+4y-4x\right)
Use the distributive property to multiply x+4 by y-x.
x^{2}+8x+16-2y\left(x-4\right)-xy+x^{2}-4y+4x
To find the opposite of xy-x^{2}+4y-4x, find the opposite of each term.
x^{2}+8x+16-2yx+8y-xy+x^{2}-4y+4x
Use the distributive property to multiply -2y by x-4.
x^{2}+8x+16-3yx+8y+x^{2}-4y+4x
Combine -2yx and -xy to get -3yx.
2x^{2}+8x+16-3yx+8y-4y+4x
Combine x^{2} and x^{2} to get 2x^{2}.
2x^{2}+8x+16-3yx+4y+4x
Combine 8y and -4y to get 4y.
2x^{2}+12x+16-3yx+4y
Combine 8x and 4x to get 12x.
x^{2}+8x+16-2y\left(x-4\right)-\left(x+4\right)\left(y-x\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+4\right)^{2}.
x^{2}+8x+16-2y\left(x-4\right)-\left(xy-x^{2}+4y-4x\right)
Use the distributive property to multiply x+4 by y-x.
x^{2}+8x+16-2y\left(x-4\right)-xy+x^{2}-4y+4x
To find the opposite of xy-x^{2}+4y-4x, find the opposite of each term.
x^{2}+8x+16-2yx+8y-xy+x^{2}-4y+4x
Use the distributive property to multiply -2y by x-4.
x^{2}+8x+16-3yx+8y+x^{2}-4y+4x
Combine -2yx and -xy to get -3yx.
2x^{2}+8x+16-3yx+8y-4y+4x
Combine x^{2} and x^{2} to get 2x^{2}.
2x^{2}+8x+16-3yx+4y+4x
Combine 8y and -4y to get 4y.
2x^{2}+12x+16-3yx+4y
Combine 8x and 4x to get 12x.