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Differentiate w.r.t. x
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\left(5\sqrt{x}\right)^{2}-\left(2y\right)^{2}
Multiplication can be transformed into difference of squares using the rule: \left(a-b\right)\left(a+b\right)=a^{2}-b^{2}.
5^{2}\left(\sqrt{x}\right)^{2}-\left(2y\right)^{2}
Expand \left(5\sqrt{x}\right)^{2}.
25\left(\sqrt{x}\right)^{2}-\left(2y\right)^{2}
Calculate 5 to the power of 2 and get 25.
25x-\left(2y\right)^{2}
Calculate \sqrt{x} to the power of 2 and get x.
25x-2^{2}y^{2}
Expand \left(2y\right)^{2}.
25x-4y^{2}
Calculate 2 to the power of 2 and get 4.