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16x^{2}+40xy+25y^{2}-12\left(4x+5y\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(4x+5y\right)^{2}.
16x^{2}+40xy+25y^{2}-48x-60y
Use the distributive property to multiply -12 by 4x+5y.
16x^{2}+40xy+25y^{2}-12\left(4x+5y\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(4x+5y\right)^{2}.
16x^{2}+40xy+25y^{2}-48x-60y
Use the distributive property to multiply -12 by 4x+5y.