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\frac{2^{6}a^{6}x^{6}}{\left(-2ax\right)^{2}}
Expand \left(2ax\right)^{6}.
\frac{64a^{6}x^{6}}{\left(-2ax\right)^{2}}
Calculate 2 to the power of 6 and get 64.
\frac{64a^{6}x^{6}}{\left(-2\right)^{2}a^{2}x^{2}}
Expand \left(-2ax\right)^{2}.
\frac{64a^{6}x^{6}}{4a^{2}x^{2}}
Calculate -2 to the power of 2 and get 4.
16a^{4}x^{4}
Cancel out 4a^{2}x^{2} in both numerator and denominator.
\frac{2^{6}a^{6}x^{6}}{\left(-2ax\right)^{2}}
Expand \left(2ax\right)^{6}.
\frac{64a^{6}x^{6}}{\left(-2ax\right)^{2}}
Calculate 2 to the power of 6 and get 64.
\frac{64a^{6}x^{6}}{\left(-2\right)^{2}a^{2}x^{2}}
Expand \left(-2ax\right)^{2}.
\frac{64a^{6}x^{6}}{4a^{2}x^{2}}
Calculate -2 to the power of 2 and get 4.
16a^{4}x^{4}
Cancel out 4a^{2}x^{2} in both numerator and denominator.