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\left(\left(-x\right)^{2}-2\left(-x\right)+1\right)\left(x-1\right)^{2}-\left(x+3\right)^{2}\left(x-3\right)^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(-x-1\right)^{2}.
\left(x^{2}-2\left(-x\right)+1\right)\left(x-1\right)^{2}-\left(x+3\right)^{2}\left(x-3\right)^{2}
Calculate -x to the power of 2 and get x^{2}.
\left(x^{2}+2x+1\right)\left(x-1\right)^{2}-\left(x+3\right)^{2}\left(x-3\right)^{2}
Multiply -2 and -1 to get 2.
\left(x^{2}+2x+1\right)\left(x^{2}-2x+1\right)-\left(x+3\right)^{2}\left(x-3\right)^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-1\right)^{2}.
x^{4}-2x^{2}+1-\left(x+3\right)^{2}\left(x-3\right)^{2}
Use the distributive property to multiply x^{2}+2x+1 by x^{2}-2x+1 and combine like terms.
x^{4}-2x^{2}+1-\left(x^{2}+6x+9\right)\left(x-3\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+3\right)^{2}.
x^{4}-2x^{2}+1-\left(x^{2}+6x+9\right)\left(x^{2}-6x+9\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-3\right)^{2}.
x^{4}-2x^{2}+1-\left(x^{4}-18x^{2}+81\right)
Use the distributive property to multiply x^{2}+6x+9 by x^{2}-6x+9 and combine like terms.
x^{4}-2x^{2}+1-x^{4}+18x^{2}-81
To find the opposite of x^{4}-18x^{2}+81, find the opposite of each term.
-2x^{2}+1+18x^{2}-81
Combine x^{4} and -x^{4} to get 0.
16x^{2}+1-81
Combine -2x^{2} and 18x^{2} to get 16x^{2}.
16x^{2}-80
Subtract 81 from 1 to get -80.
\left(\left(-x\right)^{2}-2\left(-x\right)+1\right)\left(x-1\right)^{2}-\left(x+3\right)^{2}\left(x-3\right)^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(-x-1\right)^{2}.
\left(x^{2}-2\left(-x\right)+1\right)\left(x-1\right)^{2}-\left(x+3\right)^{2}\left(x-3\right)^{2}
Calculate -x to the power of 2 and get x^{2}.
\left(x^{2}+2x+1\right)\left(x-1\right)^{2}-\left(x+3\right)^{2}\left(x-3\right)^{2}
Multiply -2 and -1 to get 2.
\left(x^{2}+2x+1\right)\left(x^{2}-2x+1\right)-\left(x+3\right)^{2}\left(x-3\right)^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-1\right)^{2}.
x^{4}-2x^{2}+1-\left(x+3\right)^{2}\left(x-3\right)^{2}
Use the distributive property to multiply x^{2}+2x+1 by x^{2}-2x+1 and combine like terms.
x^{4}-2x^{2}+1-\left(x^{2}+6x+9\right)\left(x-3\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+3\right)^{2}.
x^{4}-2x^{2}+1-\left(x^{2}+6x+9\right)\left(x^{2}-6x+9\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-3\right)^{2}.
x^{4}-2x^{2}+1-\left(x^{4}-18x^{2}+81\right)
Use the distributive property to multiply x^{2}+6x+9 by x^{2}-6x+9 and combine like terms.
x^{4}-2x^{2}+1-x^{4}+18x^{2}-81
To find the opposite of x^{4}-18x^{2}+81, find the opposite of each term.
-2x^{2}+1+18x^{2}-81
Combine x^{4} and -x^{4} to get 0.
16x^{2}+1-81
Combine -2x^{2} and 18x^{2} to get 16x^{2}.
16x^{2}-80
Subtract 81 from 1 to get -80.