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Differentiate w.r.t. c
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\left(-c^{8}\right)\left(-4\right)a^{12}bc\times 8b
To multiply powers of the same base, add their exponents. Add 6 and 6 to get 12.
\left(-c^{8}\right)\left(-4\right)a^{12}b^{2}c\times 8
Multiply b and b to get b^{2}.
\left(-c^{8}\right)\left(-32\right)a^{12}b^{2}c
Multiply -4 and 8 to get -32.
32c^{8}a^{12}b^{2}c
Multiply -1 and -32 to get 32.
32c^{9}a^{12}b^{2}
To multiply powers of the same base, add their exponents. Add 8 and 1 to get 9.