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\left(-16+2a\right)\left(-a^{2}+2a+3\right)
Calculate 4 to the power of 2 and get 16.
-16\left(-a^{2}\right)-26a-48+2a\left(-a^{2}\right)+4a^{2}
Use the distributive property to multiply -16+2a by -a^{2}+2a+3 and combine like terms.
16a^{2}-26a-48+2a\left(-a^{2}\right)+4a^{2}
Multiply -16 and -1 to get 16.
20a^{2}-26a-48+2a\left(-a^{2}\right)
Combine 16a^{2} and 4a^{2} to get 20a^{2}.
20a^{2}-26a-48+2a^{3}\left(-1\right)
To multiply powers of the same base, add their exponents. Add 1 and 2 to get 3.
20a^{2}-26a-48-2a^{3}
Multiply 2 and -1 to get -2.
\left(-16+2a\right)\left(-a^{2}+2a+3\right)
Calculate 4 to the power of 2 and get 16.
-16\left(-a^{2}\right)-26a-48+2a\left(-a^{2}\right)+4a^{2}
Use the distributive property to multiply -16+2a by -a^{2}+2a+3 and combine like terms.
16a^{2}-26a-48+2a\left(-a^{2}\right)+4a^{2}
Multiply -16 and -1 to get 16.
20a^{2}-26a-48+2a\left(-a^{2}\right)
Combine 16a^{2} and 4a^{2} to get 20a^{2}.
20a^{2}-26a-48+2a^{3}\left(-1\right)
To multiply powers of the same base, add their exponents. Add 1 and 2 to get 3.
20a^{2}-26a-48-2a^{3}
Multiply 2 and -1 to get -2.