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Differentiate w.r.t. a
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\frac{\left(-\frac{2}{3}\right)^{1}a^{4}b^{3}}{\left(-3\right)^{1}a^{1}b^{1}}
Use the rules of exponents to simplify the expression.
\frac{\left(-\frac{2}{3}\right)^{1}}{\left(-3\right)^{1}}a^{4-1}b^{3-1}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\left(-\frac{2}{3}\right)^{1}}{\left(-3\right)^{1}}a^{3}b^{3-1}
Subtract 1 from 4.
\frac{\left(-\frac{2}{3}\right)^{1}}{\left(-3\right)^{1}}a^{3}b^{2}
Subtract 1 from 3.
\frac{2}{9}a^{3}b^{2}
Divide -\frac{2}{3} by -3.
\frac{\mathrm{d}}{\mathrm{d}a}(\left(-\frac{\frac{2b^{3}}{3}}{-3b}\right)a^{4-1})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{2b^{2}}{9}a^{3})
Do the arithmetic.
3\times \frac{2b^{2}}{9}a^{3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{2b^{2}}{3}a^{2}
Do the arithmetic.