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Differentiate w.r.t. x
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\frac{z^{-3}x^{5}y^{9}}{z}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{x^{5}y^{9}}{z^{4}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{y^{5}}{z^{3}\times \frac{z}{y^{4}}}x^{-2-\left(-7\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{y^{9}}{z^{4}}x^{5})
Do the arithmetic.
5\times \frac{y^{9}}{z^{4}}x^{5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{5y^{9}}{z^{4}}x^{4}
Do the arithmetic.