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\frac{\frac{4}{8}-\frac{1}{8}}{-2}-\frac{\frac{16\times 4+1}{4}}{-4}
Least common multiple of 2 and 8 is 8. Convert \frac{1}{2} and \frac{1}{8} to fractions with denominator 8.
\frac{\frac{4-1}{8}}{-2}-\frac{\frac{16\times 4+1}{4}}{-4}
Since \frac{4}{8} and \frac{1}{8} have the same denominator, subtract them by subtracting their numerators.
\frac{\frac{3}{8}}{-2}-\frac{\frac{16\times 4+1}{4}}{-4}
Subtract 1 from 4 to get 3.
\frac{3}{8\left(-2\right)}-\frac{\frac{16\times 4+1}{4}}{-4}
Express \frac{\frac{3}{8}}{-2} as a single fraction.
\frac{3}{-16}-\frac{\frac{16\times 4+1}{4}}{-4}
Multiply 8 and -2 to get -16.
-\frac{3}{16}-\frac{\frac{16\times 4+1}{4}}{-4}
Fraction \frac{3}{-16} can be rewritten as -\frac{3}{16} by extracting the negative sign.
-\frac{3}{16}-\frac{16\times 4+1}{4\left(-4\right)}
Express \frac{\frac{16\times 4+1}{4}}{-4} as a single fraction.
-\frac{3}{16}-\frac{64+1}{4\left(-4\right)}
Multiply 16 and 4 to get 64.
-\frac{3}{16}-\frac{65}{4\left(-4\right)}
Add 64 and 1 to get 65.
-\frac{3}{16}-\frac{65}{-16}
Multiply 4 and -4 to get -16.
-\frac{3}{16}-\left(-\frac{65}{16}\right)
Fraction \frac{65}{-16} can be rewritten as -\frac{65}{16} by extracting the negative sign.
-\frac{3}{16}+\frac{65}{16}
The opposite of -\frac{65}{16} is \frac{65}{16}.
\frac{-3+65}{16}
Since -\frac{3}{16} and \frac{65}{16} have the same denominator, add them by adding their numerators.
\frac{62}{16}
Add -3 and 65 to get 62.
\frac{31}{8}
Reduce the fraction \frac{62}{16} to lowest terms by extracting and canceling out 2.