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e^{-\frac{1291.16}{0.008314\times 398}}
Multiply 8.314 and 0.001 to get 0.008314.
e^{-\frac{1291.16}{3.308972}}
Multiply 0.008314 and 398 to get 3.308972.
e^{-\frac{1291160000}{3308972}}
Expand \frac{1291.16}{3.308972} by multiplying both numerator and the denominator by 1000000.
e^{-\frac{322790000}{827243}}
Reduce the fraction \frac{1291160000}{3308972} to lowest terms by extracting and canceling out 4.