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Differentiate w.r.t. a
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16a^{6}\left(-0.125\right)^{4}
Calculate 2 to the power of 4 and get 16.
16a^{6}\times 0.000244140625
Calculate -0.125 to the power of 4 and get 0.000244140625.
0.00390625a^{6}
Multiply 16 and 0.000244140625 to get 0.00390625.
\frac{\mathrm{d}}{\mathrm{d}a}(16a^{6}\left(-0.125\right)^{4})
Calculate 2 to the power of 4 and get 16.
\frac{\mathrm{d}}{\mathrm{d}a}(16a^{6}\times 0.000244140625)
Calculate -0.125 to the power of 4 and get 0.000244140625.
\frac{\mathrm{d}}{\mathrm{d}a}(0.00390625a^{6})
Multiply 16 and 0.000244140625 to get 0.00390625.
6\times 0.00390625a^{6-1}
The derivative of ax^{n} is nax^{n-1}.
0.0234375a^{6-1}
Multiply 6 times 0.00390625.
0.0234375a^{5}
Subtract 1 from 6.