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Differentiate w.r.t. x_5
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Evaluate
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\frac{\mathrm{d}}{\mathrm{d}x_{5}}(\frac{4}{x_{5}})
Calculate 2 to the power of 2 and get 4.
-4x_{5}^{-1-1}
The derivative of ax^{n} is nax^{n-1}.
-4x_{5}^{-2}
Subtract 1 from -1.
\frac{4}{x_{5}}
Calculate 2 to the power of 2 and get 4.