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16x^{2}-16x+4-\left(2+4x\right)^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(4x-2\right)^{2}.
16x^{2}-16x+4-\left(4+16x+16x^{2}\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2+4x\right)^{2}.
16x^{2}-16x+4-4-16x-16x^{2}
To find the opposite of 4+16x+16x^{2}, find the opposite of each term.
16x^{2}-16x-16x-16x^{2}
Subtract 4 from 4 to get 0.
16x^{2}-32x-16x^{2}
Combine -16x and -16x to get -32x.
-32x
Combine 16x^{2} and -16x^{2} to get 0.
16x^{2}-16x+4-\left(2+4x\right)^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(4x-2\right)^{2}.
16x^{2}-16x+4-\left(4+16x+16x^{2}\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2+4x\right)^{2}.
16x^{2}-16x+4-4-16x-16x^{2}
To find the opposite of 4+16x+16x^{2}, find the opposite of each term.
16x^{2}-16x-16x-16x^{2}
Subtract 4 from 4 to get 0.
16x^{2}-32x-16x^{2}
Combine -16x and -16x to get -32x.
-32x
Combine 16x^{2} and -16x^{2} to get 0.