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\left(4x-8\right)^{2}-4\times 4x
Use the distributive property to multiply 4 by x-2.
16x^{2}-64x+64-4\times 4x
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(4x-8\right)^{2}.
16x^{2}-64x+64-16x
Multiply 4 and 4 to get 16.
16x^{2}-80x+64
Combine -64x and -16x to get -80x.
\left(4x-8\right)^{2}-4\times 4x
Use the distributive property to multiply 4 by x-2.
16x^{2}-64x+64-4\times 4x
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(4x-8\right)^{2}.
16x^{2}-64x+64-16x
Multiply 4 and 4 to get 16.
16x^{2}-80x+64
Combine -64x and -16x to get -80x.