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\left(x^{2}+3x+x+3\right)\left(x-4\right)\left(x-6\right)-8
Apply the distributive property by multiplying each term of x+1 by each term of x+3.
\left(x^{2}+4x+3\right)\left(x-4\right)\left(x-6\right)-8
Combine 3x and x to get 4x.
\left(x^{3}-4x^{2}+4x^{2}-16x+3x-12\right)\left(x-6\right)-8
Apply the distributive property by multiplying each term of x^{2}+4x+3 by each term of x-4.
\left(x^{3}-16x+3x-12\right)\left(x-6\right)-8
Combine -4x^{2} and 4x^{2} to get 0.
\left(x^{3}-13x-12\right)\left(x-6\right)-8
Combine -16x and 3x to get -13x.
x^{4}-6x^{3}-13x^{2}+78x-12x+72-8
Apply the distributive property by multiplying each term of x^{3}-13x-12 by each term of x-6.
x^{4}-6x^{3}-13x^{2}+66x+72-8
Combine 78x and -12x to get 66x.
x^{4}-6x^{3}-13x^{2}+66x+64
Subtract 8 from 72 to get 64.
\left(x^{2}+3x+x+3\right)\left(x-4\right)\left(x-6\right)-8
Apply the distributive property by multiplying each term of x+1 by each term of x+3.
\left(x^{2}+4x+3\right)\left(x-4\right)\left(x-6\right)-8
Combine 3x and x to get 4x.
\left(x^{3}-4x^{2}+4x^{2}-16x+3x-12\right)\left(x-6\right)-8
Apply the distributive property by multiplying each term of x^{2}+4x+3 by each term of x-4.
\left(x^{3}-16x+3x-12\right)\left(x-6\right)-8
Combine -4x^{2} and 4x^{2} to get 0.
\left(x^{3}-13x-12\right)\left(x-6\right)-8
Combine -16x and 3x to get -13x.
x^{4}-6x^{3}-13x^{2}+78x-12x+72-8
Apply the distributive property by multiplying each term of x^{3}-13x-12 by each term of x-6.
x^{4}-6x^{3}-13x^{2}+66x+72-8
Combine 78x and -12x to get 66x.
x^{4}-6x^{3}-13x^{2}+66x+64
Subtract 8 from 72 to get 64.