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Differentiate w.r.t. x
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\int \frac{2x^{4}y^{4}\times 4y^{4}\times 3x}{3x^{-3}y^{2}}\mathrm{d}x
To multiply powers of the same base, add their exponents. Add 2 and 2 to get 4.
\int \frac{2x^{5}y^{4}\times 4y^{4}\times 3}{3x^{-3}y^{2}}\mathrm{d}x
To multiply powers of the same base, add their exponents. Add 4 and 1 to get 5.
\int \frac{2x^{5}y^{8}\times 4\times 3}{3x^{-3}y^{2}}\mathrm{d}x
To multiply powers of the same base, add their exponents. Add 4 and 4 to get 8.
\int \frac{2\times 4x^{5}y^{6}}{x^{-3}}\mathrm{d}x
Cancel out 3y^{2} in both numerator and denominator.
\int 2\times 4y^{6}x^{8}\mathrm{d}x
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\int 8y^{6}x^{8}\mathrm{d}x
Multiply 2 and 4 to get 8.
8y^{6}\int x^{8}\mathrm{d}x
Factor out the constant using \int af\left(x\right)\mathrm{d}x=a\int f\left(x\right)\mathrm{d}x.
8y^{6}\times \frac{x^{9}}{9}
Since \int x^{k}\mathrm{d}x=\frac{x^{k+1}}{k+1} for k\neq -1, replace \int x^{8}\mathrm{d}x with \frac{x^{9}}{9}.
\frac{8y^{6}x^{9}}{9}
Simplify.
\frac{8y^{6}x^{9}}{9}+С
If F\left(x\right) is an antiderivative of f\left(x\right), then the set of all antiderivatives of f\left(x\right) is given by F\left(x\right)+C. Therefore, add the constant of integration C\in \mathrm{R} to the result.