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\frac{-5\left(x+2\right)}{20\left(x+2\right)^{5}}+\frac{2\times 4}{20\left(x+2\right)^{5}}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of 4\left(x+2\right)^{4} and 5\left(x+2\right)^{5} is 20\left(x+2\right)^{5}. Multiply \frac{-1}{4\left(x+2\right)^{4}} times \frac{5\left(x+2\right)}{5\left(x+2\right)}. Multiply \frac{2}{5\left(x+2\right)^{5}} times \frac{4}{4}.
\frac{-5\left(x+2\right)+2\times 4}{20\left(x+2\right)^{5}}
Since \frac{-5\left(x+2\right)}{20\left(x+2\right)^{5}} and \frac{2\times 4}{20\left(x+2\right)^{5}} have the same denominator, add them by adding their numerators.
\frac{-5x-10+8}{20\left(x+2\right)^{5}}
Do the multiplications in -5\left(x+2\right)+2\times 4.
\frac{-5x-2}{20\left(x+2\right)^{5}}
Combine like terms in -5x-10+8.
\frac{-5x-2}{20x^{5}+200x^{4}+800x^{3}+1600x^{2}+1600x+640}
Expand 20\left(x+2\right)^{5}.
\frac{-5\left(x+2\right)}{20\left(x+2\right)^{5}}+\frac{2\times 4}{20\left(x+2\right)^{5}}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of 4\left(x+2\right)^{4} and 5\left(x+2\right)^{5} is 20\left(x+2\right)^{5}. Multiply \frac{-1}{4\left(x+2\right)^{4}} times \frac{5\left(x+2\right)}{5\left(x+2\right)}. Multiply \frac{2}{5\left(x+2\right)^{5}} times \frac{4}{4}.
\frac{-5\left(x+2\right)+2\times 4}{20\left(x+2\right)^{5}}
Since \frac{-5\left(x+2\right)}{20\left(x+2\right)^{5}} and \frac{2\times 4}{20\left(x+2\right)^{5}} have the same denominator, add them by adding their numerators.
\frac{-5x-10+8}{20\left(x+2\right)^{5}}
Do the multiplications in -5\left(x+2\right)+2\times 4.
\frac{-5x-2}{20\left(x+2\right)^{5}}
Combine like terms in -5x-10+8.
\frac{-5x-2}{20x^{5}+200x^{4}+800x^{3}+1600x^{2}+1600x+640}
Expand 20\left(x+2\right)^{5}.