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Evaluate
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Differentiate w.r.t. x
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\frac{x^{-4}z^{-2}y^{2}}{x^{-2}z^{6}}
Cancel out y^{4} in both numerator and denominator.
\frac{y^{2}}{x^{2}z^{8}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{y^{6}}{z^{2}y^{4}z^{6}}x^{-4-\left(-2\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{y^{2}}{z^{8}}x^{-2})
Do the arithmetic.
-2\times \frac{y^{2}}{z^{8}}x^{-2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{2y^{2}}{z^{8}}\right)x^{-3}
Do the arithmetic.