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Differentiate w.r.t. n
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\frac{n^{8}}{n^{24}}
To raise a power to another power, multiply the exponents. Multiply 6 and 4 to get 24.
\frac{1}{n^{16}}
Rewrite n^{24} as n^{8}n^{16}. Cancel out n^{8} in both numerator and denominator.
\frac{\mathrm{d}}{\mathrm{d}n}(\frac{n^{8}}{n^{24}})
To raise a power to another power, multiply the exponents. Multiply 6 and 4 to get 24.
\frac{\mathrm{d}}{\mathrm{d}n}(\frac{1}{n^{16}})
Rewrite n^{24} as n^{8}n^{16}. Cancel out n^{8} in both numerator and denominator.
-\left(n^{16}\right)^{-1-1}\frac{\mathrm{d}}{\mathrm{d}n}(n^{16})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
-\left(n^{16}\right)^{-2}\times 16n^{16-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-16n^{15}\left(n^{16}\right)^{-2}
Simplify.