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Differentiate w.r.t. x
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\frac{5}{3}\times \frac{4}{5}x^{\frac{5}{3}-1}
The derivative of ax^{n} is nax^{n-1}.
\frac{4}{3}x^{\frac{5}{3}-1}
Multiply \frac{5}{3} times \frac{4}{5} by multiplying numerator times numerator and denominator times denominator. Then reduce the fraction to lowest terms if possible.
\frac{4}{3}x^{\frac{2}{3}}
Subtract 1 from \frac{5}{3}.