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Differentiate w.r.t. x
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\frac{3x^{2}y^{-3}z^{4}}{y^{5}x^{2}z^{3}\times 2xz^{-3}}
To multiply powers of the same base, add their exponents. Add 1 and 4 to get 5.
\frac{3x^{2}y^{-3}z^{4}}{y^{5}x^{3}z^{3}\times 2z^{-3}}
To multiply powers of the same base, add their exponents. Add 2 and 1 to get 3.
\frac{3x^{2}y^{-3}z^{4}}{y^{5}x^{3}\times 2}
Multiply z^{3} and z^{-3} to get 1.
\frac{3y^{-3}z^{4}}{2xy^{5}}
Cancel out x^{2} in both numerator and denominator.
\frac{3z^{4}}{2xy^{8}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{3z^{4}}{y^{3}\times \frac{2xyz^{3}y^{4}}{z^{3}}}x^{2-2})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{3z^{4}}{2xy^{8}}x^{0})
Do the arithmetic.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{3z^{4}}{2xy^{8}})
For any number a except 0, a^{0}=1.
0
The derivative of a constant term is 0.