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\frac{1}{8}-\frac{4}{162}
Reduce the fraction \frac{3}{24} to lowest terms by extracting and canceling out 3.
\frac{1}{8}-\frac{2}{81}
Reduce the fraction \frac{4}{162} to lowest terms by extracting and canceling out 2.
\frac{81}{648}-\frac{16}{648}
Least common multiple of 8 and 81 is 648. Convert \frac{1}{8} and \frac{2}{81} to fractions with denominator 648.
\frac{81-16}{648}
Since \frac{81}{648} and \frac{16}{648} have the same denominator, subtract them by subtracting their numerators.
\frac{65}{648}
Subtract 16 from 81 to get 65.