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Differentiate w.r.t. a
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\frac{27a^{-3}b^{1}}{3^{-4}a^{2}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{27b^{1}}{3^{-4}a^{5}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{27b}{3^{-4}a^{5}}
Calculate b to the power of 1 and get b.
\frac{27b}{\frac{1}{81}a^{5}}
Calculate 3 to the power of -4 and get \frac{1}{81}.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{27}{b^{2}\times \frac{1}{81b^{3}}}a^{-3-2})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}a}(2187ba^{-5})
Do the arithmetic.
-5\times 2187ba^{-5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-10935b\right)a^{-6}
Do the arithmetic.