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Differentiate w.r.t. u
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\frac{25^{1}u^{1}v^{1}}{40^{1}u^{4}v^{1}}
Use the rules of exponents to simplify the expression.
\frac{25^{1}}{40^{1}}u^{1-4}v^{1-1}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{25^{1}}{40^{1}}u^{-3}v^{1-1}
Subtract 4 from 1.
\frac{25^{1}}{40^{1}}\times \frac{1}{u^{3}}v^{0}
Subtract 1 from 1.
\frac{25^{1}}{40^{1}}\times \frac{1}{u^{3}}
For any number a except 0, a^{0}=1.
\frac{5}{8}\times \frac{1}{u^{3}}
Reduce the fraction \frac{25}{40} to lowest terms by extracting and canceling out 5.
\frac{\mathrm{d}}{\mathrm{d}u}(\frac{25v}{40v}u^{1-4})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}u}(\frac{5}{8}u^{-3})
Do the arithmetic.
-3\times \frac{5}{8}u^{-3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-\frac{15}{8}u^{-4}
Do the arithmetic.