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\frac{2}{45}-\frac{1}{x+5}
Multiply 1 and 45 to get 45.
\frac{2\left(x+5\right)}{45\left(x+5\right)}-\frac{45}{45\left(x+5\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of 45 and x+5 is 45\left(x+5\right). Multiply \frac{2}{45} times \frac{x+5}{x+5}. Multiply \frac{1}{x+5} times \frac{45}{45}.
\frac{2\left(x+5\right)-45}{45\left(x+5\right)}
Since \frac{2\left(x+5\right)}{45\left(x+5\right)} and \frac{45}{45\left(x+5\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{2x+10-45}{45\left(x+5\right)}
Do the multiplications in 2\left(x+5\right)-45.
\frac{2x-35}{45\left(x+5\right)}
Combine like terms in 2x+10-45.
\frac{2x-35}{45x+225}
Expand 45\left(x+5\right).