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\frac{-4}{12\times \frac{4}{3}+\frac{5}{12}\times \frac{4}{3}}
Divide 12 by \frac{3}{4} by multiplying 12 by the reciprocal of \frac{3}{4}.
\frac{-4}{\frac{12\times 4}{3}+\frac{5}{12}\times \frac{4}{3}}
Express 12\times \frac{4}{3} as a single fraction.
\frac{-4}{\frac{48}{3}+\frac{5}{12}\times \frac{4}{3}}
Multiply 12 and 4 to get 48.
\frac{-4}{16+\frac{5}{12}\times \frac{4}{3}}
Divide 48 by 3 to get 16.
\frac{-4}{16+\frac{5\times 4}{12\times 3}}
Multiply \frac{5}{12} times \frac{4}{3} by multiplying numerator times numerator and denominator times denominator.
\frac{-4}{16+\frac{20}{36}}
Do the multiplications in the fraction \frac{5\times 4}{12\times 3}.
\frac{-4}{16+\frac{5}{9}}
Reduce the fraction \frac{20}{36} to lowest terms by extracting and canceling out 4.
\frac{-4}{\frac{144}{9}+\frac{5}{9}}
Convert 16 to fraction \frac{144}{9}.
\frac{-4}{\frac{144+5}{9}}
Since \frac{144}{9} and \frac{5}{9} have the same denominator, add them by adding their numerators.
\frac{-4}{\frac{149}{9}}
Add 144 and 5 to get 149.
-4\times \frac{9}{149}
Divide -4 by \frac{149}{9} by multiplying -4 by the reciprocal of \frac{149}{9}.
\frac{-4\times 9}{149}
Express -4\times \frac{9}{149} as a single fraction.
\frac{-36}{149}
Multiply -4 and 9 to get -36.
-\frac{36}{149}
Fraction \frac{-36}{149} can be rewritten as -\frac{36}{149} by extracting the negative sign.