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Differentiate w.r.t. z
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\frac{z^{4}}{\left(z^{6}\right)^{8}}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
\frac{z^{4}}{z^{48}}
To raise a power to another power, multiply the exponents. Multiply 6 and 8 to get 48.
\frac{1}{z^{44}}
Rewrite z^{48} as z^{4}z^{44}. Cancel out z^{4} in both numerator and denominator.
\frac{\mathrm{d}}{\mathrm{d}z}(\frac{z^{4}}{\left(z^{6}\right)^{8}})
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
\frac{\mathrm{d}}{\mathrm{d}z}(\frac{z^{4}}{z^{48}})
To raise a power to another power, multiply the exponents. Multiply 6 and 8 to get 48.
\frac{\mathrm{d}}{\mathrm{d}z}(\frac{1}{z^{44}})
Rewrite z^{48} as z^{4}z^{44}. Cancel out z^{4} in both numerator and denominator.
-\left(z^{44}\right)^{-1-1}\frac{\mathrm{d}}{\mathrm{d}z}(z^{44})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
-\left(z^{44}\right)^{-2}\times 44z^{44-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-44z^{43}\left(z^{44}\right)^{-2}
Simplify.