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Differentiate w.r.t. z
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\frac{2^{4}\left(z^{\frac{1}{5}}\right)^{4}}{z^{\frac{1}{20}}}
Expand \left(2z^{\frac{1}{5}}\right)^{4}.
\frac{2^{4}z^{\frac{4}{5}}}{z^{\frac{1}{20}}}
To raise a power to another power, multiply the exponents. Multiply \frac{1}{5} and 4 to get \frac{4}{5}.
\frac{16z^{\frac{4}{5}}}{z^{\frac{1}{20}}}
Calculate 2 to the power of 4 and get 16.
16z^{\frac{3}{4}}
Cancel out \sqrt[20]{z} in both numerator and denominator.
\frac{\mathrm{d}}{\mathrm{d}z}(\frac{2^{4}\left(z^{\frac{1}{5}}\right)^{4}}{z^{\frac{1}{20}}})
Expand \left(2z^{\frac{1}{5}}\right)^{4}.
\frac{\mathrm{d}}{\mathrm{d}z}(\frac{2^{4}z^{\frac{4}{5}}}{z^{\frac{1}{20}}})
To raise a power to another power, multiply the exponents. Multiply \frac{1}{5} and 4 to get \frac{4}{5}.
\frac{\mathrm{d}}{\mathrm{d}z}(\frac{16z^{\frac{4}{5}}}{z^{\frac{1}{20}}})
Calculate 2 to the power of 4 and get 16.
\frac{\mathrm{d}}{\mathrm{d}z}(16z^{\frac{3}{4}})
Cancel out \sqrt[20]{z} in both numerator and denominator.
\frac{3}{4}\times 16z^{\frac{3}{4}-1}
The derivative of ax^{n} is nax^{n-1}.
12z^{\frac{3}{4}-1}
Multiply \frac{3}{4} times 16.
12z^{-\frac{1}{4}}
Subtract 1 from \frac{3}{4}.