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Differentiate w.r.t. s
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\frac{2^{-2}\left(r^{5}\right)^{-2}\left(s^{-3}\right)^{-2}\times \left(7r^{-3}s^{5}\right)^{0}}{\left(\left(-r^{4}\right)s^{-3}\right)^{3}}
Expand \left(2r^{5}s^{-3}\right)^{-2}.
\frac{2^{-2}r^{-10}\left(s^{-3}\right)^{-2}\times \left(7r^{-3}s^{5}\right)^{0}}{\left(\left(-r^{4}\right)s^{-3}\right)^{3}}
To raise a power to another power, multiply the exponents. Multiply 5 and -2 to get -10.
\frac{2^{-2}r^{-10}s^{6}\times \left(7r^{-3}s^{5}\right)^{0}}{\left(\left(-r^{4}\right)s^{-3}\right)^{3}}
To raise a power to another power, multiply the exponents. Multiply -3 and -2 to get 6.
\frac{\frac{1}{4}r^{-10}s^{6}\times \left(7r^{-3}s^{5}\right)^{0}}{\left(\left(-r^{4}\right)s^{-3}\right)^{3}}
Calculate 2 to the power of -2 and get \frac{1}{4}.
\frac{\frac{1}{4}r^{-10}s^{6}\times 1}{\left(\left(-r^{4}\right)s^{-3}\right)^{3}}
Calculate 7r^{-3}s^{5} to the power of 0 and get 1.
\frac{\frac{1}{4}r^{-10}s^{6}}{\left(\left(-r^{4}\right)s^{-3}\right)^{3}}
Multiply \frac{1}{4} and 1 to get \frac{1}{4}.
\frac{\frac{1}{4}r^{-10}s^{6}}{\left(-r^{4}\right)^{3}\left(s^{-3}\right)^{3}}
Expand \left(\left(-r^{4}\right)s^{-3}\right)^{3}.
\frac{\frac{1}{4}r^{-10}s^{6}}{\left(-r^{4}\right)^{3}s^{-9}}
To raise a power to another power, multiply the exponents. Multiply -3 and 3 to get -9.
\frac{\frac{1}{4}r^{-10}s^{15}}{\left(-r^{4}\right)^{3}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\frac{1}{4}r^{-10}s^{15}}{\left(-1\right)^{3}\left(r^{4}\right)^{3}}
Expand \left(-r^{4}\right)^{3}.
\frac{\frac{1}{4}r^{-10}s^{15}}{\left(-1\right)^{3}r^{12}}
To raise a power to another power, multiply the exponents. Multiply 4 and 3 to get 12.
\frac{\frac{1}{4}r^{-10}s^{15}}{-r^{12}}
Calculate -1 to the power of 3 and get -1.
\frac{\frac{1}{4}s^{15}}{-r^{22}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.